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Early results of an active Phase II clinical trial show promise in maintaining or improving vision in wet AMD. The treatment, developed by Regeneron and called VEGF-Trap-Eye, is an injection into the eye.
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Researchers in Canada have taken a look at cataract development and report that the use of certain anti-depression medications may contribute to cataract growth.
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One of the most exciting avenues of research for macular degeneration involves the use of the stem cells to treat vision loss. Researchers at the University of California, Irvine, have made important progress towards this goal. In the online Journal of Neuroscience Methods, they report that they have created an eight-layer, early stage retina from human embryonic stem cells.
Other UCI researchers, funded by Discovery Eye Foundation, are using the adult human retina to regenerate damaged tissue. In this approach, the person's own stem cells could be recruited to provide an avenue for restored vision.
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ARVO(Association for Research in Vision and Ophthalmology) was formed in 1928 and has been holding scientific meetings for decades. Each May, thousands of scientists gather to share their research through presentations and posters.
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A comprehensive dilated eye exam is a painless procedure in which an eye care professional examines your eyes to look for common vision problems and eye diseases, many of which have no early warning signs. Regular comprehensive eye exams can help you protect your sight and make sure that you are seeing your best.
A comprehensive eye examination includes:
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By: Bill Takeshita, OD
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Prescription filters are one of the most important visual aids that people with macular degeneration will benefit from wearing. The ultra-violet radiation and blue wavelengths of light can potentially damage the cells of the retina and too much light can actually reduce a person's ability to see, especially under very bright sunlight.
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This issue is a particularly sensitive one for seniors who also have macular degeneration or other conditions that impair their vision. Driving means independence and most people want to hold on to their cars as long as possible. When is it time to stop?
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One of the most common questions submitted to AMD.org is whether cataract surgery is safe for someone with macular degeneration. Patients worry that having the surgery may worsen their macular degeneration. Fortunately, we now have recent research to answer that question. The simple answer is, yes, you can have that cataract removed.
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The National Eye Institute just released this information about an ongoing study of gene therapy for Leber congenital amaurosis, a retinal disease affecting younger people. Although this research was conducted with people who did not have age-related macular degeneration, the results are encouraging for similar therapies for AMD. All three subjects had maintained their previous visual gains.
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MacuSight is currently recruiting patients with wet AMD for a Phase 2 study of an ocular sirolimus formulation in combination with Lucentis®. This is a randomized, multi-center study and is taking place throughout the United States.
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For the first time, researchers have been able to link "specific food intake patterns with substantial AMD risk reductions". They used the data from the AREDS (Age-related Eye Disease Study) research, which included about 4,000 patients.
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We've known for a long time that nutrition plays a role in macular degeneration. While we don't have all the answers yet, new information keeps adding to our understanding.
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If you are being treated for wet macular degeneration with Avastin injections, you may want to talk to your doctor about blood pressure.
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The promise of gene therapy is renewed with the announcement that partial vision has been restored to three individuals with retinal disease.
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Early reports are encouraging from a small study of patients with dry macular degeneration or retinitis pigmentosa. Seven of the 10 people in the study showed improved visual acuity. |
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Sirion Therapeutics announced positive interim results from their Phase II clinical trial of fenretinide. It is being used for patients who have an advanced form of dry macular degeneration called geographic atrophy (GA).
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Research is uncovering some intriguing information about cataracts and why they develop. It has been known that exposure to sunlight UV rays can promote the development of cataracts (wear those sunglasses!). This seems to be because ultraviolet light triggers the production of damaging free radicals inside the eye.
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The final one-year results from Cohort 1 of the SAILOR Clinical Trial show that Lucentis was not associated with a higher rate of stroke. Last year, concerns were raised when early data indicated that injections of 0.5 mg. of Lucentis had a four times higher incidence of stroke than the 0.3 mg injection.
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Does alcohol affect AMD? For years, research has hinted that red wine may actually help, but beer may be something to avoid.
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Stress can contribute to many health issues - creating them, making them worse, or just making it harder to cope with them. Some people with macular degeneration mention that they feel their vision is worse when they are very stressed.
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