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Bevasiranib – Gene Silencing

Phase I and Phase II trials of Bevasiranib have been completed and a Phase III clinical trial is now recruiting.

TG100801Eye Drops – Targegen

The Phase I clinical trial involved 44 healthy volunteers without AMD. It was designed to assess the safety and tolerance of the eye drop. No data is yet available.

PTK787 Pill for AMD – Novartis

This Phase I/II study looked at the safety and tolerance of a tablet of Vitalanib, taken over three months and the effect on wet macular degeneration. The study is completed and no data is available as yet.

Talaporfin Sodium PDT – Light Sciences LLC

This Phase I trial was undertaken to determine the safety of photodynamic therapy (PDT), using the drug talaporfin sodium (LS11). Twenty-seven patients were enrolled and the study was completed in January 2006. No data is available.